"It just touched on really basic human emotions, like a life blueprint. ‘I don't have any friends. I feel isolated.' Those sort of core human emotions," Emma Caulfield, Anya on the series, said.

Taking part in the squee-inducing reunion: Whedon, Gellar, Caulfield, Amber Benson, Alyson Hannigan, David Boreanaz, James Marsters, Seth Green, Charisma Carpenter, Michelle Trachtenberg, Kristine Sutherland, Alexis Denisof and Nicholas Brendon.

"I'm so incredibly proud of what we all created," Gellar said. "Sometimes you need distance to really understand the gravitas of that. I appreciate everything about that job. As an actor, all you ever want to do is leave your mark — you want to do something that affects people.